Composition: Erdanib-4: Each film coated tablet contains Erdafitinib INN 4.00 mg. Erdanib-5: Each film coated tablet contains Erdafitinib INN 5.00 mg. Pharmacology: Erdafitinib is a kinase inhibitor that binds to and inhibits enzymatic activity of FGFR1, FGFR2, FGFR3 and FGFR4 based on in vitro data. Erdafitinib also binds to RET, CSF1R, PDGFRA, PDGFRB, FLT4, KIT, and VEGFR2. Erdafitinib inhibited FGFR phosphorylation and signaling and decreased cell viability in cell lines expressing FGFR genetic alterations, including point mutations, amplification, and fusions. Erdafitinib demonstrated antitumor activity in FGFR-expressing cell lines and xenograft models derived from tumor types, including bladder cancer. Pharmacokinetics: Following administration of 8 mg once daily,
Additional Information:
- Item Code: er01
- Production Capacity: 5
- Delivery Time: 5 DAYS
- Packaging Details: 60'S